Factors Affecting the Secretion of Staphylococcal Enterotoxin A
نویسندگان
چکیده
منابع مشابه
Factors affecting the secretion of staphylococcal enterotoxin A.
The biosynthesis of enterotoxin A by replicating and nonreplicating cells was investigated. Unlike enterotoxin B, a secondary metabolite, enterotoxin A secretion resembled that of a primary metabolite by being secreted during the exponential phase of growth. The amount of toxin produced per unit of growth was not influenced by NaCl, NaNO(2), or NaNO(3). Several surfactants increased toxin secre...
متن کاملFactors affecting the regulation of staphylococcal enterotoxin B.
Several factors which regulate the synthesis of enterotoxin B were examined in Staphylococcus aureus S-6 and in its heme-requiring mutant S-6H2. The kinetics of enterotoxin B synthesis during anaerobic growth were identical to those observed under aerobic conditions; extracellular enterotoxin accumulated in the medium during the transition between exponential and stationary phase growth. Strain...
متن کاملThe staphylococcal enterotoxin (SE) family
Staphylococcus aureus plays an important role in numerous human cases of food poisoning, soft tissue, and bone infections, as well as potentially lethal toxic shock. This common bacterium synthesizes various virulence factors that include staphylococcal enterotoxins (SEs). These protein toxins bind directly to major histocompatibility complex class II on antigen-presenting cells and specific Vβ...
متن کاملStaphylococcal enterotoxin microbial superantigens.
Staphylococcal enterotoxins are a family of structurally related proteins that are produced by Staphylococcus aureus. In addition to their role in the pathogenicity of food poisoning, these microbial superantigens have profound effects on the immune system, which makes them useful tools for understanding its mechanism of action. These molecules (24-30 kDa) are highly hydrophilic and exhibit low...
متن کاملTransport and processing of staphylococcal enterotoxin A.
A larger-molecular-weight precursor of enterotoxin A was found in membranes of Staphylococcus aureus and was shown to be the kinetic precursor to the extracellular form of the toxin. Subcellular fractionation revealed that mature enterotoxin A was transiently associated with the cell wall before being released to the extracellular environment.
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ژورنال
عنوان ژورنال: Applied Microbiology
سال: 1970
ISSN: 0003-6919
DOI: 10.1128/aem.20.3.492-496.1970